Homepage   Symptoms Database   Patient Questionnaire
MeCP2.org.uk logo

About MeCP2

MeCP2 & Rett Syndrome
MeCP2 Protein Structure

Databases

Symptoms Database
Mutation Frequency

Patient Questionnaire

Rett Links

RS Research Foundation
RS Association UK
RS Europe
International RS Association

ISCR

MeCP2.org.uk is hosted at the ISCR, Edinburgh University, Scotland

Contact Us

info@mecp2.org.uk

Our Terms and Conditions.

Website design and development by....

Millband

Search Symptoms Database


CLICK FOR HELP
Select ONE of the Search Methods Below:

By All MeCP2 Mutations:


By Selected MeCP2 Mutation:

Multiple selections are allowed.

Windows/Linux users hold down either the Ctrl or Shift key.

Mac users hold down either the Apple or Shift key.


By Mutations within an MeCP2 Protein Domain:      MBD :    TRD :


MeCP2 Domain Map

By Mutations within an Amino Acid Range:      N Term AA:    C Term AA:

Use this Page to Refine Your Search:

Refine the Search by Phenotype Score(s) (optional):

For a list of symptom codes see the panel to the right.
Symptoms are scored between 0 and 2 where 0 is mild and 2 is severe.

eg, ((SI = 2 AND RH = 2) OR SF = 0)

The above condition would refine the search to patients who suffer badly from both seizures and repeatative hand movement or those patients who do not suffer from unusually small feet.

Refine the Search by Patient Age (optional):

Use the keyword AGE and the following condition statements to build your refinement. < less than, > greater than, <> not equal to, = equal to.
REMEMBER that age is given to 1 decimal place - therefore to find 3 yr olds use (AGE > 3 AND AGE < 4)

eg, ((AGE < 10 AND AGE >= 3 AND AGE <> 5)

The above condition would refine the search to patients with the following ages: 3,4,6,7,8,9

Select How to Display the Search Results:

Display Fields:

Amino Acid Number:  

Base Pair Mutation:  

Amino Acid Mutation:  

Mutation Type:  

Patient Age:  

Select Symptoms Score Fields To Display:

Multiple selections are allowed.

Symptom Codes are listed in the panel to the right.


Display All Symptoms:

Process the Results Further to Determine and Display:

Global Average of All KNOWN Symptom Scores per Patient Entry:
Average of DISPLAYED Symptom Scores per Patient Entry:

Symptom Codes

AEAbnormal EEG
ABSLAbnormal sleep patterns
AMAmbulatory
BIBreathing irregularities
COConstipation
DHDecreasing head cirumference
EDEating difficulties
GIGI reflux
GRGrowth retardation
IAIrritability/agitation
LPLoss of purposeful hand motions
MRMuscle rigidity/spasticity
NVNon verbal
PNPeriod of normal development
PCPoor circulation
RHRepetitive hand motions
SCScolosis
SESeizures
SISelf injurious behaviours
SFSmall feet
TGTeeth grinding
TRTremors